PV-0241: Comparing endpoints of radiation induced lung injury for NSCLC: radiology vs. clinical symptoms
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چکیده
منابع مشابه
Establishment of a rat model of radiation-induced lung injury
Background: Radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. Materials and Methods: 50 female Wistar rats were randomly divided into 5 groups, average 10 rats/cage: A. control group B. 3Gy×10f C. 6Gy×5f D. 12.5Gy×1f E.15.3Gy×1f....
متن کاملRadiation-induced Lung Injury
membrane, and are just wide enough to allow the passage of red blood cells, one cell at a time. The alveoli are lined with specialized epithelial cells termed Type I pneumocytes. Interspersed among these cells are surfactant-producing Type II pneumocytes. Within the alveolar wall, pneumocytes are separated from endothelial cells by their associated basement membranes and a potential stromal spa...
متن کاملestablishment of a rat model of radiation-induced lung injury
background: radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. materials and methods: 50 female wistar rats were randomly divided into 5 groups, average 10 rats/cage: a. control group b. 3gy×10f c. 6gy×5f d. 12.5gy×1f e.15.3gy×1f. by different doses of r...
متن کاملThe Evaluation of Melatonin Effect Against The Early Effect of Ionizing Radiation Induced Lung Injury
Background & Objective: Lung is a radiosensitive organ. Patients who are undergoing radiation therapy in their chest are subjected to radiation pneumonitis in the early phase and pulmonary fibrosis in the late one. Melatonin scavenges free radicals directly and acts as an indirect antioxidant through the activation of major antioxidant enzymes as well. The aim of the study thus is to investiga...
متن کاملProtective effect of vitamin D on radiation-induced lung injury: Experimental evidence
Background: Vitamin D, especially its most active metabolite 1,25-dihydroxyvitamin D₃(Vit D) is essential in regulating a wide variety of biologic processes, such as regulating mesangial cell activation. The objective of this study was to assess the histopathological changes of effectiveness of Vit D as a protective agent against radiation induced lung injury. Materials and Methods: Eighteen Wi...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2017
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(17)30684-9